Morphine is an incredibly addictive drug. Without the help of morphine addiction treatment centers TX trusts, it's hard for clients to break out of addiction's vicious cycle. Fortunately, The Right Step offers morphine rehab centers in Texas to help individuals begin a new life. What is Morphine? Morphine (M, Miss Emma, Monkey, White Stuff, God\u2019s Drug, MS, Morf, Morpho, Dreamer, First Line, Emsel, Unkie, and Mister Blue) is the most abundant opiate (narcotic) analgesic found in opium. It is a potent pain reliever used legally in the clinical setting, although it is also abused illicitly. Morphine is an opium agonist, which means it blocks the transmission of pain signals to the brain by binding to nervous system proteins called opioid receptors. The U.S. Food and Drug Administration (FDA) first approved morphine in 1941. Multiple companies manufacture the drug under different brand names.1,2,3\u00a0Some of the clinical applications of morphine include: \tPost-surgery \tAfter major trauma or injury, except head injuries \tIn advanced, terminal cancers for severe pain \tTo reduce severe coughing associated with lung cancer The oral solution of morphine (Roxanol) with the highest concentration (100 mg per 5 ml) and Avinza capsules containing 90 mg should be prescribed only to people who are opioid-tolerant or used to the effects of opioids. Morphine may cause severely low blood pressure in people who have low blood volume, anemia or who were administered general anesthetics or an antipsychotic class of drug called phenothiazines. Morphine is contradicted for head injuries and intracranial pressure because taking it may exaggerate the drug\u2019s respiratory depressant effects and further increase intracranial pressure.1 It is a major contributor to the rise of prescription drug abuse centers across the US to combat the growing epidemic. Brief History of Morphine In the early 19th\u00a0century, a pharmacist\u2019s assistant named Friedrich Wilhelm Serturner isolated a yellowish-white crystalline compound from crude opium after immersing it in ammoniated hot water. He observed small doses resulted in pain relief and euphoria, while high doses could lead to psychiatric effects, nausea, vomiting, cough suppression, constipation and slowed breathing. Pain relief was 10 times greater than that of opium. Serturner named the compound morphine, after the Greek God of dreams, Morpheus. It was discovered that morphine was more addictive than either alcohol or opium, although accounts of as many as 400,000 American Civil War soldiers being addicted to morphine have been largely debunked. There is not a single report during the Civil War of a soldier using morphine for pleasure and a neurologist at the time berated the medical profession for its reluctance to administer morphine to soldiers with gruesome wounds. The first documented use of the phrase \u201csoldier\u2019s disease\u201d was associated with World War I in 1915.3,4 Morphine Addiction Treatment Centers TX Morphine can be highly effective in managing severe pain, although its euphoric effects, the potential for tolerance and severe withdrawal symptoms are associated with a high risk of addiction and relapse. It's a deadly combination that makes morphine addiction treatment centers TX offers an essential commodity. Morphine directly targets the central nervous system and changes the way in which the body feels and responds to pain. Like other opioids, it binds to opiate receptors in the brain and changes the neurochemical activity in the brainstem, thereby altering some automatic body functions. It also impacts regions in the brain responsible for pleasure, binding to opiate receptors within the reward pathways. Specific reinforcing brain patterns may develop as a person obsesses over taking the drug, causing them to compulsively seek it out. A number of studies have provided an improved understanding of morphine addiction by clarifying the morphine-specific functional and molecular changes in multiple reward-related brain regions.5,6 Misusing morphine by taking excessive doses or combining it with street drugs, alcohol or other prescription drugs can have dangerous consequences and may be fatal. Treatment for morphine addiction, whether through an intensive outpatient program or inpatient rehab center in Texas, is challenging. It becomes even more difficult with co-occurring use of other illicit and prescription drugs, whether intentional or unintentional. Most experts recommend\u00a0medical detox center in Texas\u00a0due to the severity of morphine withdrawal symptoms and risk of relapse.6 Morphine Rehab Centers Texas Stats and Facts \tEmergency department (ED) visits involving morphine increased by 120% from 15,762 visits in 2005 to 34,593 visits in 2011, although no changes occurred between 2007 and 2011.7 \tAmong females, ED visits for morphine doubled from 2005 to 2011.7 \tMorphine ED visits by age group in 2011 were as follows: 4,347 (ages 18 to 25); 3,444 (ages 26 to 34); 4,757 (ages 35 to 44); 8,228 (ages 45 to 54) and 12,984 (ages 55 and older).7 \tNatural opioids (including morphine and codeine) and semi-synthetic opioids (including commonly prescribed pain medications such as oxycodone and hydrocodone) were involved in more than 12,700 deaths in 2015.8 Relapse Prevention and Morphine Addiction Treatment TX Overcoming addiction is extremely challenging and the risk of relapse is high. A promising study from the University of Minnesota Medical School, Department of Neuroscience identified a potential target for preventing morphine relapse in mice. This research pinpointed two different types of dopamine-receptive neurons (D1 and D2) located in the brain\u2019s nucleus accumbens that could be driving addictive behavior. This part of the brain plays a role in motivation and reinforcement. In mice with repeated morphine use, researchers found D1 activity persistently increased while D2 activity decreased, implying dopamine-receptor cells may trigger a relapse. By retuning D1 through manipulation, they were able to stop morphine relapse in the mice. Further studies are needed to assess the potential efficacy of this approach in humans. Identifying the mechanisms triggering relapse in humans is key to developing more efficacious addiction treatment modalities.9 We apply these same ideals to our relapse prevention program in Texas so our clients can feel secure in the state of their recovery. \tWhat Is Morphine? Everyday Health website.\u00a0https:\/\/www.everydayhealth.com\/drugs\/morphine\u00a0Updated January 12, 2015. Accessed February 15, 2017. \tWhat is Morphine? News Medical website.\u00a0https:\/\/www.news-medical.net\/health\/What-is-Morphine.aspx\u00a0Updated October 27, 2013. Accessed February 15, 2017. \tMorphine History. News Medical website.\u00a0https:\/\/www.news-medical.net\/health\/Morphine-History.aspx\u00a0Updated October 27, 2013. Accessed February 15, 2017. \tThe Mythical Roots of U.S. Drug Policy: Soldier\u2019s Disease and Addiction in the Civil War. DRC Net Library website.\u00a0https:\/\/www.druglibrary.org\/schaffer\/history\/soldis.htm\u00a0Accessed February 15, 2017. \tLong term effects of morphine on the brain (INFOGRAPHIC). Addiction Blog website.\u00a0https:\/\/addictionblog.org\/infographics\/long-term-effects-of-morphine-on-the-brain-infographic\/\u00a0Accessed February 15, 2017. \tMorphine Abuse. Drug Abuse website.\u00a0https:\/\/drugabuse.com\/library\/morphine-abuse\/\u00a0Accessed February 15, 2017. \tThe CBHSQ Report: Emergency Department Visits Involving Narcotic Pain Relievers. Substance Abuse and Mental Health Services Administration website.\u00a0https:\/\/www.samhsa.gov\/data\/sites\/default\/files\/report_2083\/ShortReport-2083.html\u00a0Published November 5, 2015. Accessed February 15, 2017. \tNew data show continuing opioid epidemic in the United States. Centers for Disease Control and Prevention website.\u00a0https:\/\/www.cdc.gov\/media\/releases\/2016\/p1216-continuing-opioid-epidemic.html\u00a0Published December 16, 2016. Accessed February 15, 2017. \tResearch snapshot: New tools could help prevent relapse behavior in opioid addiction. University of Minnesota website.\u00a0https:\/\/www.healthtalk.umn.edu\/2016\/01\/29\/new-tools-prevent-morphine-relapse-mndrive\/\u00a0Published January 29, 2016. Accessed February 15, 2017. Written by The Right Step Editorial Staff Contact our Texas center today for more information on our treatment programs.